2R7B: Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor

PDB ID: 2R7BDownload
MMDB ID: 66555
PDB Deposition Date: 2007/9/7
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 2R7B: monomeric; determined by author and by software (PISA)
Molecular Components in 2R7B
Label Count Molecule
Protein (1 molecule)
1
3-phosphoinositide-dependent Protein Kinase 1
(Gene symbol: PDPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
SULFATE IONSULFATE ION
2
1
10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine
3
1
Molecule information is not available.
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303